IVF treatment has been long in use to fertilize human eggs outside of the body and it is usually the first line of treatment. The key difference between conventional IVF and Intracytoplasmic Sperm Injection (ICSI) is the way the eggs are being fertilised in the laboratory.
In conventional IVF, eggs collected from the woman are left in a petri dish with millions of sperm for natural fertilization to happen on its own.
Less invasive form of egg fertilization compared to ICSI
Less chance of egg damage due to human manipulation error
Natural selection of sperm – survival of the fittest
Higher chance of Total Fertilization Failure
No control over multiple sperm entry into the egg
Not useful in couples with male infertility factor
No information on egg maturity after retrieval
Intracytoplasmic Sperm Injection (ICSI)
However, in ICSI, a single mature egg is subjected to microinjection of a single sperm to achieve fertilization.
This step is very crucial to the survival of the injected egg as it requires a lot of skill of an Embryologist.